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Parameters Value
Complication rates and costs
Base Case & Scenario 1:
Complication rate (usual care) 6.20%
Complication cost per patient (usual care) HKD 106,523.39
Cost per “healthy” patient, aged 45–54 (usual care) HKD 5,705.28
Cost per “healthy” patient, aged 55–64 (usual care) HKD 9,293.30
Cost per “healthy” patient, aged 65–74 (usual care) HKD 15,137.81
Scenario 2:
Complication rate (RAMP) 3.81%
Complication cost per patient (RAMP) HKD 123,363.56
Cost per “healthy” patient, aged 45–54 (RAMP) HKD 5,950.20
Cost per “healthy” patient, aged 55–64 (RAMP) HKD 9,538.22
Cost per “healthy” patient, aged 65–74 (RAMP) HKD 15,382.73
Cost of intervention for diagnosed DM patients (Scenario 1, 2) HKD 3,486.00
Screening
Scenario 1 & 2: screening cost per head HKD 200
Screening interval (per year)
Prediabetes screening interval 1
Low-risk (no DM) screening interval 1/3
High-risk (no DM) screening interval 1

Risk level prevalence
Low-risk (no DM) aged 45–54 58.80%
Low risk (no DM) aged 55–64 56.50%
Low-risk (no DM) aged 65–74 52.70%
Mortality rates
Overall mortality rate for aged 45–54 0.21%
Overall mortality rate for aged 55–64 0.46%
Overall mortality rate for aged 65–74 1.09%
Base Case & Scenario 1:
Mortality rate specific to DM for aged 45–54 0.85%
Mortality rate specific to DM for aged 55–64 1.86%
Mortality rate specific to DM for aged 65–74 4.27%
Scenario 2:
Mortality rate specific to DM for aged 45–54 (RAMP care) 0.32%
Mortality rate specific to DM for aged 55–64 (RAMP care) 0.69%
Mortality rate specific to DM for aged 65–74 (RAMP care) 1.59%
Mortality rate specific to prediabetes for aged 45–54 0.50%
Mortality rate specific to prediabetes for aged 55–64 0.60%
Mortality rate specific to prediabetes for aged 65–74 0.70%

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