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Table 4.14
                                  Number of individuals at each diagnostic state per five-year intervals
                                  (Scenario 1)

                                                  2022     2026    2031     2036     2041     2046    2051
                                  “Healthy”
                                  population    1,031,809  989,631  947,101  903,765  867,155  816,363  771,369
                                  Prediabetes    13,992   66,380  108,803  134,833  151,022  159,604  162,967
                                  population
                                  DM population  82,599   63,198   52,321   47,129  46,361   42,876   41,631


                             Consequently, under Scenario 1 where all individuals in the target age demographic undergo
                             screening, the cost of complications (including the cost of additional intervention subsidies to
                             diagnosed patients) decreases relative to the Base Scenario (Figure 4.12b). In particular, the
                             cost of complications for individuals is markedly lower in Scenario 1. This lower cost is the
                             result of fewer patients with DM after the implementation of screening and basic lifestyle
                             modification.

                             Within Scenario 1, after the implementation and adoption of the screening programme,
                             we project that there will be cost savings to the health system compared to having no
                             screening (Base Scenario). In particular, our BIA forecasts a total spending of
                             HKD 31.36 billion over the 30-year horizon. This translates to a 30.84%
                             savings in costs relative to the Base Scenario (Table 4.16). The projected savings
                             over the 30-year period amount to HKD 13.98 billion.

                                     Total cost of DM care (Scenario 1) = [Screening cost] + [Intervention cost] +
                                          [Complications care] + [Care for patients without complications]


                             Scenario 2
                             Relative to Scenario 1, there are more individuals in the prediabetes and DM population at
                             the end of the 30-year horizon despite similar rates of change for disease progression and
                             remission (Figure 4.11) (Table 4.15). This result is due to a lower mortality rate specific to DM,
                             thus allowing more individuals to progress through the different diagnostic states of DM.



































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